منابع مشابه
Genetic Factors in Schizophrenia Risk
Recent findings Multiple and variable genetic and environmental factors interact to influence the risk of schizophrenia. Both rare variants with large effect and common variants with small effect contribute to genetic risk of schizophrenia, with no indication for differential impact on its clinical features. Accumulating evidence supports a genetic architecture of schizophrenia with multiple sc...
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Biochemical, immunological and epidemiological evidence increasingly support the suggestion that there is a causal relationship between gluten/gliadin and schizophrenia as originally proposed by F. C. Dohan. Furthermore the necessary physiological mechanisms exist to explain a mechanism involving bioactive peptides from these proteins, and these show that this mechanism is possible and probable...
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Background: Schizophrenia is a polygenic mental disorder with about 80% heritability. Growing evidence indicated that synaptic dysfunctions contribute to SCZ etiopathogenesis. The context and purpose of the study: Transcription factors play an important role in the regulation of gene expression. Whereas expression analysis of transcription factor has been performed, studies of their genetic var...
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Sir, On the basis of the data that they had collected, Parmeshwaran et al.(1999) concluded that a significant relationship exists between phases of the lunar synodic cycle and the development of psychiatric morbidity. From a methodological perspective, I have a reservation about their validity of their conclusions : Parmeshwaran et al.(1999) studied patients at the time of admission and not at ...
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One of the defining characteristics of schizophrenia is impaired social functioning. This was recognized a century ago in the earliest clinical descriptions of the disorder. Today, deterioration of social relations remains a hallmark of schizophrenia, with social isolation and withdrawal forming part of its clinical profile in the Diagnostic and Statistical Manual of Mental Disorders. But what ...
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ژورنال
عنوان ژورنال: Journal of Medical Genetics
سال: 1973
ISSN: 1468-6244
DOI: 10.1136/jmg.10.4.400-a